The impact of lung volume recruitment on pulmonary function in progressive childhood-onset neuromuscular disease: a systematic review

O'Sullivan, Rachel, Carrier, Judith ORCID: https://orcid.org/0000-0002-2657-2280, Cranney, Helen and Hemming, Rebecca ORCID: https://orcid.org/0000-0002-8708-5638 2021. The impact of lung volume recruitment on pulmonary function in progressive childhood-onset neuromuscular disease: a systematic review. Archives of Physical Medicine and Rehabilitation 102 (5) , pp. 976-983. 10.1016/j.apmr.2020.07.014

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Abstract

Objectives The focus of this systematic review was to consider whether lung volume recruitment (LVR) has an effect on pulmonary function test parameters in individuals with progressive childhood-onset neuromuscular diseases. The review was registered on PROSPERO (No. CRD42019119541). Data Sources A systematic search of the CINAHL, MEDLINE, AMED, EMCARE, Scopus, and Open Grey databases was undertaken in January 2019 considering LVR in the respiratory management of childhood-onset neuromuscular diseases. Study Selection Studies were included if either manual resuscitator bags or volume-controlled ventilators were used to perform LVR with participants older than 6 years of age. Critical appraisal tools from the Joanna Briggs Institute were used to assess the quality of studies. Nine studies were identified, 6 of which were of sufficient quality to be included in the review. Data Extraction Data extraction used a tool adapted from the Cochrane effective practice and organization of care group. Data Synthesis Results were compiled using a narrative synthesis approach focused on peak cough flow, forced vital capacity, and maximum inspiratory capacity outcomes. Conclusions Limited evidence suggests an immediate positive effect of LVR on peak cough flow and a potential long-term effect on the rate of forced vital capacity decline. Considering the accepted correlation between forced vital capacity and morbidity, this review suggests that LVR be considered for individuals with childhood-onset neuromuscular diseases once forced vital capacity starts to deteriorate. This review is limited by small sample sizes and the overall paucity of evidence considering LVR in this population group. Controlled trials with larger sample sizes are urgently needed.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Healthcare Sciences
Publisher:	Elsevier
ISSN:	0003-9993
Date of First Compliant Deposit:	4 September 2020
Date of Acceptance:	29 July 2020
Last Modified:	09 Nov 2023 18:50
URI:	https://orca.cardiff.ac.uk/id/eprint/134661

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