New developments in telomere length analysis

Baird, Duncan Martin ORCID: https://orcid.org/0000-0001-8408-5467 2005. New developments in telomere length analysis. Experimental Gerontology 40 (5) , pp. 363-368. 10.1016/j.exger.2005.02.008

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Abstract

Telomeres provide an essential 'capping' function, which prevents the natural end of a chromosome from being recognised as a simple dsDNA break. The biology of human telomeres is inextricably linked with both cancer and ageing. As such there is considerable interest in determining the length of these essential and dynamic structures. Here I review, from the standpoint of ageing research in humans, the current situation with regards to technologies available to determine telomere length in human cells and tissues.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Uncontrolled Keywords:	Telomerase activity; Tumour progression; Q-FISH
Publisher:	Elsevier
ISSN:	0531-5565
Last Modified:	21 Oct 2022 09:53
URI:	https://orca.cardiff.ac.uk/id/eprint/38165

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