Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Genetic testing of children for adult-onset conditions: opinions of the British adult population and implications for clinical practice

Shkedi-Rafid, Shiri, Fenwick, Angela, Dheensa, Sandi and Lucassen, Anneke M 2014. Genetic testing of children for adult-onset conditions: opinions of the British adult population and implications for clinical practice. European Journal of Human Genetics 23 (10) , pp. 1281-1285. 10.1038/ejhg.2014.221

Full text not available from this repository.

Abstract

This study set out to explore the attitudes of a representative sample of the British public towards genetic testing in children to predict disease in the future. We sought opinions about genetic testing for adult-onset conditions for which no prevention/treatment is available during childhood, and about genetic ‘carrier’ status to assess future reproductive risks. The study also examined participants’ level of agreement with the reasons professional organisations give in favour of deferring such testing. Participants (n=2998) completed a specially designed questionnaire, distributed by email. Nearly half of the sample (47%) agreed that parents should be able to test their child for adult-onset conditions, even if there is no treatment or prevention at time of testing. This runs contrary to professional guidance about genetic testing in children. Testing for carrier status was supported by a larger proportion (60%). A child’s future ability to decide for her/himself if and when to be tested was the least supported argument in favour of deferring testing.

Item Type: Article
Date Type: Published Online
Status: Published
Schools: Social Sciences (Includes Criminology and Education)
Publisher: Nature Publishing Goup
ISSN: 1018-4813
Date of Acceptance: 1 September 2014
Last Modified: 05 Nov 2019 03:35
URI: http://orca.cardiff.ac.uk/id/eprint/104903

Citation Data

Cited 12 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item