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Bronchiectasis following treatment for high-risk neuroblastoma: A case series

Adams, Madeleine, Traunecker, Heidi, Doull, Iolo and Cox, Rachel 2017. Bronchiectasis following treatment for high-risk neuroblastoma: A case series. Pediatric Blood and Cancer 64 (10) , e26509. 10.1002/pbc.26509

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High‐risk (HR) neuroblastoma remains a very challenging disease to treat and long‐term cure is only possible with intensive, multimodal treatment including chemotherapy, high‐dose therapy, radiotherapy, surgery, and immunotherapy. As a result, treatment‐related morbidity and late effects are common in survivors. This report outlines a case series of six patients who developed a chronic productive cough following treatment for HR neuroblastoma. High‐resolution computed tomography scanning confirmed the diagnosis of bronchiectasis. Two of the patients who have undergone immunological testing demonstrate hypogammaglobulinaemia and impaired vaccine response. Persistent cough in patients treated for neuroblastoma warrants investigation and consideration of immunological referral.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Wiley
ISSN: 1545-5009
Date of Acceptance: 7 February 2017
Last Modified: 17 Jul 2019 12:54

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