Morgan, Ian Rhys ORCID: https://orcid.org/0000-0002-0253-1855, Yazici, Arife, Pyne, Stephen G. and Skelton, Brian W. 2008. Diastereoselective Ritter Reactions of Chiral CyclicN-Acyliminium Ions: Synthesis of Pyrido- and Pyrrolo[2,3-d]oxazoles and 4-Hydroxy-5-N-acylaminopyrrolidines and 5-Hydroxy-6-N-acylaminopiperidines. Journal of Organic Chemistry 73 (7) , pp. 2943-2946. 10.1021/jo800007g |
Official URL: http://dx.doi.org/10.1021/jo800007g
Abstract
Pyrido- and pyrrolo[2,3-d]oxazoles can be conveniently prepared in high yield from the Ritter reaction of nitriles and in situ generated chiral cyclic N-acyliminium ions. cis-4-Hydroxy-5-acylaminopyrrolidines and cis-5-hydroxy-6-acylaminopiperidines can be readily obtained by acid hydrolysis of these bicyclic heterocyclic compounds, respectively.
Item Type: | Article |
---|---|
Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Subjects: | Q Science > QD Chemistry |
Publisher: | ACS |
ISSN: | 0022-3263 |
Last Modified: | 24 Oct 2022 11:29 |
URI: | https://orca.cardiff.ac.uk/id/eprint/48278 |
Citation Data
Cited 25 times in Scopus. View in Scopus. Powered By Scopus® Data
Actions (repository staff only)
Edit Item |