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A pilot study on the assessment of upper airway obstruction in patients undergoing tonsillectomy with or without adenoidectomy

Bathala, Srinivasalu 2013. A pilot study on the assessment of upper airway obstruction in patients undergoing tonsillectomy with or without adenoidectomy. MPhil Thesis, Cardiff University.
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Abstract

Adenotonsillectomy is currently indicated as a treatment for sleep-­‐related breathing disorders in children because removal of the tonsils opens up the airway and lowers airway resistance to breathing. Overnight pulse oximetry and polysomnography are two common investigations used to diagnose sleep-­‐related breathing disorders, but these are overnight and time-­‐consuming procedures. This thesis proposes that a simple non-­‐invasive measurement of peak inspiratory flow rates may help in decision-­‐making towards patient selection for surgical treatment of sleep-­‐related breathing disorders. Since the upper airway cause of any sleep-­‐related breathing disorder is believed to be obstruction of oral and nasal airways due to enlarged tonsils or adenoids, it seems reasonable that patient selection for surgery could be better managed by simple measurements of the severity of airway obstruction rather than the consequences of this obstruction as determined by overnight studies This thesis investigates the severity of upper airway obstruction in patients undergoing tonsillectomy +/-­‐ adenoidectomy by measuring peak nasal and oral inspiratory airflow (PNIF, POIF). The study was conducted in two phases: the first phase on the day of surgery and the second phase approximately one month after surgery. Fifty subjects were recruited for the first phase of the study from a cohort of patients on the waiting list for tonsillectomy with or without adenoidectomy at University Hospital Wales. Twenty-­‐five of these subjects were followed up in the second phase of the study at the Common Cold Centre. All the subjects were instructed to perform three measurements of both peak nasal and oral flow during both visits. 9 This study demonstrated that a simple non-­‐invasive inspiratory flow meter could be used to measure both POIF and PNIF. Postoperative POIF and PNIF had increased compared to the preoperative POIF and PNIF, and this difference was statistically significant

Item Type: Thesis (MPhil)
Status: Unpublished
Schools: Biosciences
Subjects: R Medicine > R Medicine (General)
Last Modified: 10 Oct 2017 15:17
URI: https://orca.cardiff.ac.uk/id/eprint/52113

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