Thomas, Gethin Owain 2006. Smart screens for thyroid disrupting substances in the environment. PhD Thesis, Cardiff University. |
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Abstract
The interaction of recombinant TR with TRE-containing double-stranded DNA duplexes was monitored using the electrophoretic shift assay (EMSA). A protein titration allowed the calculation of the K& of TR for DNA. This quantitation of the affinity of TR for DNA was subsequently measured in the presence of known T3 analogues, thus providing the basis of a TR-DNA binding assay.
Item Type: | Thesis (PhD) |
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Status: | Unpublished |
Schools: | Medicine |
Subjects: | R Medicine > R Medicine (General) |
Funders: | Biotechnology and Biological Sciences Research Council (BBSRC), MLT Research Ltd |
Date of First Compliant Deposit: | 30 March 2016 |
Last Modified: | 12 Feb 2016 23:11 |
URI: | https://orca.cardiff.ac.uk/id/eprint/54105 |
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