Haematological prognostic indices after myocardial infarction: evidence from the diet and reinfarction trial (DART)

Burr, Michael Leslie, Holiday, R. M., Fehily, A. M. and Whitehead, P. J. 1992. Haematological prognostic indices after myocardial infarction: evidence from the diet and reinfarction trial (DART). European Heart Journal 13 (2) , pp. 166-170.

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Abstract

Data from the Diet and Reinfarction Trial were examined to check the prognostic effects of plasma fibrinogen, plasma viscosity, white blood cell count, haemoglobin and mean platelet volume in 92 deaths among 1755 men who had recently recovered from acute myocardial infarction. All these variables were significantly associated with all-cause mortality over the following 18 months (haemoglobin negatively, the others positively). Those who gave up smoking following their infarct had a lower mortality than those who continued to smoke (4.1% and 7.9% respectively), and this effect appeared to be mediated by fibrinogen levels. Smoking habit accounted for only part of the prognostic effect of fibrinogen and white blood cell count. Haematological variables have an important prognostic significance after myocardial infarction. Cessation of smoking after myocardial infarction is worthwhile and has a favourable effect on plasma fibrinogen.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine
Publisher:	Oxford University Press
ISSN:	0195-668X
Related URLs:	http://eurheartj.oxfordjournals.org/
Last Modified:	04 May 2016 03:20
URI:	https://orca.cardiff.ac.uk/id/eprint/72105

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