Kolasinski, James ORCID: https://orcid.org/0000-0002-1599-6440, Makin, Tamar R., Logan, John P., Jbabdi, Saad, Clare, Stuart, Stagg, Charlotte J. and Johansen-Berg, Heidi 2016. Perceptually relevant remapping of human somatotopy in 24 hours. eLife 5 , e17280. 10.7554/eLife.17280.001 |
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Abstract
Experience-dependent reorganisation of functional maps in the cerebral cortex is well described in the primary sensory cortices. However, there is relatively little evidence for such cortical reorganisation over the short-term. Using human somatosensory cortex as a model, we investigated the effects of a 24 hr gluing manipulation in which the right index and right middle fingers (digits 2 and 3) were adjoined with surgical glue. Somatotopic representations, assessed with two 7 tesla fMRI protocols, revealed rapid off-target reorganisation in the non-manipulated fingers following gluing, with the representation of the ring finger (digit 4) shifted towards the little finger (digit 5) and away from the middle finger (digit 3). These shifts were also evident in two behavioural tasks conducted in an independent cohort, showing reduced sensitivity for discriminating the temporal order of stimuli to the ring and little fingers, and increased substitution errors across this pair on a speeded reaction time task.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Psychology |
Subjects: | B Philosophy. Psychology. Religion > BF Psychology |
Additional Information: | This article is distributed under the terms of the Creative Commons Attribution License. |
Publisher: | eLife Sciences Publications |
ISSN: | 2050-084X |
Date of First Compliant Deposit: | 30 January 2017 |
Date of Acceptance: | 29 December 2016 |
Last Modified: | 06 May 2023 01:56 |
URI: | https://orca.cardiff.ac.uk/id/eprint/97870 |
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