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Continuous flow synthesis of antimalarials: opportunities for distributed autonomous chemical manufacturing

Howard, Joseph L., Schotten, Christiane and Browne, Duncan L. 2017. Continuous flow synthesis of antimalarials: opportunities for distributed autonomous chemical manufacturing. Reaction Chemistry and Engineering 2 (3) , pp. 281-287. 10.1039/C7RE00034K

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Abstract

The concept of distributed manufacturing of chemicals is presented and discussed, with specific focus on the context of preparing molecules that can combat the development of geographically-localised resistant strains of infectious pathogens. Specifically we present the case of antimalarial compounds and demonstrate that the flow chemistry community have already designed both a machine capable of distrubuted chemical manufacturing and a module that would be capable of producing artemisin derivatives at the point of use.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: Royal Society of Chemistry
ISSN: 2058-9883
Date of First Compliant Deposit: 10 April 2017
Date of Acceptance: 29 March 2017
Last Modified: 06 Jan 2021 02:37
URI: http://orca.cardiff.ac.uk/id/eprint/99783

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