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Decarboxylation as the key step in C−C bond‐forming reactions

Patra, Tuhin and Maiti, Debabrata 2017. Decarboxylation as the key step in C−C bond‐forming reactions. Chemistry - A European Journal 23 (31) , pp. 7382-7401. 10.1002/chem.201604496

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C−C bond forming reactions incarnate the core of organic synthesis because of their fundamental applications to molecular diversity and complexity. In recent years, use of carboxylic acid as one of the coupling partners in place of conventional organometallic reagents has seen an upsurge due to its potency to generate similar organometallic intermediates after decarboxylation. This Review provides an overview on the most recent progress in the field of C−C bond formation involving decarboxylation as a key step. Different important developments, which are not included in earlier Reviews in this area, have been summarized with representative examples and discussions on their reaction mechanisms.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Publisher: Wiley
ISSN: 0947-6539
Date of Acceptance: 18 November 2016
Last Modified: 06 May 2023 01:58

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