Cooper, Miriam  ORCID: https://orcid.org/0000-0002-4695-5481, Thapar, Anita ORCID: https://orcid.org/0000-0002-3689-737X and Jones, Derek ORCID: https://orcid.org/0000-0003-4409-8049
2014.
Erratum to: White matter microstructure predicts autistic traits in Attention-Deficit/Hyperactivity Disorder.
Journal of Autism and Developmental Disorders
44
(11)
, p. 2755.
10.1007/s10803-014-2162-2
|
Abstract
Traits of autism spectrum disorder (ASD) in children with attention-deficit/hyperactivity disorder (ADHD) have previously been found to index clinical severity. This study examined the association of ASD traits with diffusion parameters in adolescent males with ADHD (n = 17), and also compared WM microstructure relative to controls (n = 17). Significant associations (p < 0.05, corrected) were found between fractional anisotropy/radial diffusivity and ASD trait severity (positive and negative correlations respectively), mostly in the right posterior limb of the internal capsule/corticospinal tract, right cerebellar peduncle and the midbrain. No case-control differences were found for the diffusion parameters investigated. This is the first report of a WM microstructural signature of autistic traits in ADHD. Thus, even in the absence of full disorder, ASD traits may index a distinctive underlying neurobiology in ADHD.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) Cardiff University Brain Research Imaging Centre (CUBRIC) Medicine Neuroscience and Mental Health Research Institute (NMHRI) Psychology |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Publisher: | Springer |
| ISSN: | 0162-3257 |
| Last Modified: | 28 Oct 2022 09:32 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/74866 |
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