The role of the multidisciplinary team in antifungal stewardship

Agrawal, Samir, Barnes, Rosemary, Brüggemann, Roger J., Rautemaa-Richardson, Riina and Warris, Adilia 2016. The role of the multidisciplinary team in antifungal stewardship. Journal of Antimicrobial Chemotherapy 71 (Supp 2) , ii37-ii42. 10.1093/jac/dkw395

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Abstract

There are a variety of challenges faced in the management of invasive fungal diseases (IFD), including high case-fatality rates, high cost of antifungal drugs and development of antifungal resistance. The diagnostic challenges and poor outcomes associated with IFD have resulted in excessive empirical use of antifungals in various hospital settings, exposing many patients without IFD to potential drug toxicities as well as causing spiralling antifungal drug costs. Further complexity arises as different patient groups show marked variation in their risk for IFD, fungal epidemiology, sensitivity and specificity of diagnostic tests and the pharmacokinetics and pharmacodynamics of antifungal drugs. To address these issues and to ensure optimal management of IFD, specialist knowledge and experience from a range of backgrounds is required, which extends beyond the remit of most antibiotic stewardship programmes. The first step in the development of any antifungal stewardship (AFS) programme is to build a multidisciplinary team encompassing the necessary expertise in the management of IFD to develop and implement the AFS programme. The specific roles of the key individuals within the AFS team and the importance of collaboration are discussed in this article.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Oxford University Press
ISSN:	0305-7453
Date of First Compliant Deposit:	8 June 2017
Date of Acceptance:	22 September 2016
Last Modified:	12 May 2020 15:00
URI:	https://orca.cardiff.ac.uk/id/eprint/101303

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