SAXS4COLL: an integrated software tool for analysing fibrous collagen-based tissues

Abass, Ahmed, Bell, James Stephen ORCID: https://orcid.org/0000-0001-8371-9851, Spang, Martin T., Hayes, Sally ORCID: https://orcid.org/0000-0001-8550-0108, Meek, Keith Michael Andrew ORCID: https://orcid.org/0000-0002-9948-7538 and Boote, Craig ORCID: https://orcid.org/0000-0003-0348-6547 2017. SAXS4COLL: an integrated software tool for analysing fibrous collagen-based tissues. Journal of Applied Crystallography 50 , pp. 1235-1240. 10.1107/S1600576717007877

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Abstract

This article provides an overview of a new integrated software tool for reduction and analysis of small-angle X-ray scattering (SAXS) data from fibrous collagen tissues, with some wider applicability to other cylindrically symmetric scattering systems. SAXS4COLL combines interactive features for data pre-processing, bespoke background subtraction, semi-automated peak detection and calibration. Both equatorial and meridional SAXS peak parameters can be measured, and the former can be deconstructed into cylinder and lattice contributions. Finally, the software combines functionality for determination of collagen spatial order parameters with a rudimentary orientation plot capability.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Optometry and Vision Sciences
Subjects:	R Medicine > RE Ophthalmology
Publisher:	International Union of Crystallography
ISSN:	0021-8898
Funders:	MRC
Date of First Compliant Deposit:	12 June 2017
Date of Acceptance:	26 May 2017
Last Modified:	06 May 2023 00:12
URI:	https://orca.cardiff.ac.uk/id/eprint/101384

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