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Generalised musculoskeletal problems

Baerwald, Christoph and Choy, Ernest 2019. Generalised musculoskeletal problems. Best Practice & Research Clinical Rheumatology 33 (3) , 101441. 10.1016/j.berh.2019.101441

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The last decades have witnessed enormous progress in understanding the pathogenic mechanisms of rheumatic diseases. Based on these findings new paradigms in the treatment of many rheumatic diseases could be established leading to an improvement in the outcome of rheumatic diseases that was not conceivable at the end of the last century. However, in recent years many studies revealed a gap between the perceived (and measured) disease activity and various other parameters best summarized as patient reported outcomes (PRO). The PRO such as pain, fatigue, sleep quality and quality of life are getting more attention since regulatory agencies, e.g. FDA as well as EMA, require PRO to be included in clinical studies for approval of new treatments.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Elsevier
ISSN: 1521-6942
Date of First Compliant Deposit: 21 November 2019
Date of Acceptance: 1 May 2019
Last Modified: 07 Dec 2020 18:45

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