Antibiotic exposure and the risk of colorectal adenoma and carcinoma: a systematic review and meta-analysis of observational studies

Sanyaolu, L. N. ORCID: https://orcid.org/0000-0002-6762-6986, Oakley, N. J., Nurmatov, U. ORCID: https://orcid.org/0000-0002-9557-8635, Dolwani, S. ORCID: https://orcid.org/0000-0002-3113-5472 and Ahmed, H. ORCID: https://orcid.org/0000-0002-0634-8548 2020. Antibiotic exposure and the risk of colorectal adenoma and carcinoma: a systematic review and meta-analysis of observational studies. Colorectal Disease 22 (8) , pp. 858-870. 10.1111/codi.14921

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Abstract

The Incidence of colorectal cancer (CRC) is increasing, and evidence suggests that maladaptation of the bowel microbiome may be associated with colorectal carcinogenesis. Consumption of antibiotics may cause imbalance of the bowel microbiome but research assessing an association between antibiotic exposure and CRC is inconsistent. The aim of this systematic review and meta‐analysis was to appraise and synthesize the available evidence.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	Wiley
ISSN:	1462-8910
Date of First Compliant Deposit:	25 November 2019
Date of Acceptance:	17 November 2019
Last Modified:	09 Nov 2024 06:15
URI:	https://orca.cardiff.ac.uk/id/eprint/127105

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