Why we need a core outcome set for trials of interventions for prevention and management of caries

Lamont, Thomas, Schwendicke, Falk and Innes, Nicola ORCID: https://orcid.org/0000-0002-9984-0012 2015. Why we need a core outcome set for trials of interventions for prevention and management of caries. Evidence-Based Dentistry 16 (3) , pp. 66-68. 10.1038/sj.ebd.6401109

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Abstract

Although the research process, extending from primary evidence creation through to guideline production for delivery at the point of care, should functionally act as a continuum, it consists of different stages. There are many points along this route at which research can fail to deliver its promises of improved patient care. One of these is where the findings of clinical trials cannot be compared to, or combined with, other trials. Failure to combine trials into systematic reviews, with or without meta-analyses, means it is not possible to determine the relative overall benefit of a particular intervention with any certainty. This can hamper the uptake of new evidence into practice or might prevent discontinuing use of an ineffective treatment.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Dentistry
Publisher:	Nature Publishing Group
ISSN:	1462-0049
Last Modified:	07 Nov 2022 11:05
URI:	https://orca.cardiff.ac.uk/id/eprint/134467

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