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Combined use of rotational and excimer lASER coronary atherectomy ( RASER ) during complex coronary angioplasty-An analysis of cases (2006-2016) from the British Cardiovascular Intervention Society database

Protty, Majd B, Gallagher, Sean, Farooq, Vasim, Sharp, Andrew S. P., Egred, Mohaned, O'Kane, Peter and Kinnaird, Tim 2021. Combined use of rotational and excimer lASER coronary atherectomy ( RASER ) during complex coronary angioplasty-An analysis of cases (2006-2016) from the British Cardiovascular Intervention Society database. Catheterization and Cardiovascular Interventions 97 (7) , E911-E918. 10.1002/ccd.29377
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Abstract

Introduction Combining rotational (RA) and excimer laser coronary atherectomy (ELCA)—RASER atherectomy—is technique utilized in the percutaneous management of calcific coronary disease. The evidence base examining its safety and utility is sparse and limited to small case‐series. This study examines the patterns and outcomes of RASER atherectomy use in the largest cohort to date. Methods Using the British Cardiac Intervention Society database, data were analyzed on all PCI procedures in the UK between 2006 and 2016. Descriptive statistics and multivariate logistic regressions were used to examine baseline, procedural, and outcome associations with RASER. Results We identified 153 (0.02%) RASER atherectomy cases out of 686,358 PCI procedures. Baseline covariates associated with RASER use were age, BMI, diabetes, stable coronary disease, and previous CABG. Procedural co‐variates associated with RASER were CTO‐PCI, the use of more/longer stents, intravascular imaging, cutting balloons, and microcatheters. Adjusted rates of in‐hospital major adverse cardiac/cerebrovascular events (MACCE) were not significantly different with RASER. However, there were higher odds of arterial complications (OR 3.23, 95% CI: 1.58–6.61), slow flow (OR 3.50, 95% CI: 1.29–9.55), and shock induction (OR 9.66, 95% CI: 3.44–27.06). Conclusions RASER atherectomy use in complex PCI is associated with higher risk baseline and procedural characteristics. Although increased rates of shock induction, slow flow, and arterial complications were observed, RASER does not increase the likelihood of in‐hospital MACCE, major bleeding, or death.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Wiley
ISSN: 1522-1946
Date of First Compliant Deposit: 23 September 2021
Date of Acceptance: 22 October 2020
Last Modified: 11 Oct 2021 16:19
URI: http://orca.cardiff.ac.uk/id/eprint/137528

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