BKC-2, a new BKC variant detected in MCR-9.1-producing Enterobacter hormaechei subsp. xiangfangensis

Martins, Willames M. B. S., Martins, Evelin R., de Andrade, Letícia K., Farzana, Refath, Walsh, Timothy R., Toleman, Mark A. ORCID: https://orcid.org/0000-0002-9497-0512, Nogueira, Mara C. L. and Gales, Ana C. 2021. BKC-2, a new BKC variant detected in MCR-9.1-producing Enterobacter hormaechei subsp. xiangfangensis. Antimicrobial Agents and Chemotherapy 65 (3) , e01193-20. 10.1128/AAC.01193-20

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Abstract

We performed the characterization of a multidrug-resistant (MDR) Enterobacter spp. isolate highlighting the genetic aspects of the antimicrobial resistance genes. An Enterobacter spp. isolate (Ec61) was recovered in 2014 from a transtracheal aspirate sample from a patient admitted to a Brazilian tertiary hospital and submitted to further microbiological and genomic characterization. Ec61 was identified as Enterobacter hormaechei subsp. xiangfangensis ST451, showed a MDR profile and the presence of genes codifying new β-lactamase variants, BKC-2 and ACT-84, and the mobile colistin resistance gene mcr-9.1.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	American Society for Microbiology
ISSN:	0066-4804
Date of First Compliant Deposit:	6 January 2023
Date of Acceptance:	3 December 2020
Last Modified:	04 May 2023 11:03
URI:	https://orca.cardiff.ac.uk/id/eprint/138252

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