Verma, Shalini, Mishra, Pawan K. ![]() |
Official URL: http://dx.doi.org/10.1021/acs.joc.8b00980
Abstract
An efficient approach for the synthesis of functionalized tetrahydro-pyrido/quinolinocarbazoles from 2-alkynylindole-3-carbaldehydes and l-proline utilizing a metal-free decarboxylative cyclization, ring expansion, and ring contraction strategy via the generation of azomethine ylide was developed. The reaction of 2-alkynylindole-3-carbaldehydes with l-thioproline leads to the formation of γ-carbolines. By virtue of this expedient method, a diverse range of biologically active heteroannulated carbazoles can be synthesized efficiently.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Publisher: | American Chemical Society |
ISSN: | 0022-3263 |
Last Modified: | 09 Nov 2022 10:59 |
URI: | https://orca.cardiff.ac.uk/id/eprint/141413 |
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