Phosphoramidate nucleoside derivatives as anticancer agents

NuCana PLC 2021. Phosphoramidate nucleoside derivatives as anticancer agents. WO2017207986A1; US20210130387A1. [Patent].

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Abstract

This invention relates to derivatives of cladribine. The compounds are phosphoramidate derivatives in which the phosphoramidate moiety is situated on the 3′-hydroxyl group of cladribine. The invention also relates to pharmaceutical formulations of the cladribine derivatives and their use in methods of treatment. The compounds are useful in the treatment of cancer.

Item Type:	Patent
Date Type:	Publication
Status:	Published
Schools:	Pharmacy
Last Modified:	29 Nov 2022 09:42
URI:	https://orca.cardiff.ac.uk/id/eprint/144353

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