Riglin, Lucy, Wootton, Robyn, Livingston, Lucy ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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Abstract
Objective: We investigated whether “late-onset” ADHD that emerges in adolescence/adulthood is similar in risk factor profile to: (1) child-onset ADHD, but emerges later because of scaffolding/compensation from childhood resources; and (2) depression, because it typically onsets in adolescence/adulthood and shows symptom and genetic overlaps with ADHD. Methods: We examined associations between late-onset ADHD and ADHD risk factors, cognitive tasks, childhood resources and depression risk factors in a population-based cohort followed-up to age 25 years (N=4224–9764). Results: Parent-rated late-onset ADHD was like child-onset persistent ADHD in associations with ADHD polygenic risk scores and cognitive task performance, although self-rated late-onset ADHD was not. Late-onset ADHD was associated with higher levels of childhood resources than child-onset ADHD and did not show strong evidence of association with depression risk factors. Conclusions: Late-onset ADHD shares characteristics with child-onset ADHD when parent-rated, but differences for self-reports require investigation. Childhood resources may delay the onset of ADHD.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Medicine Psychology MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) |
Publisher: | SAGE Publications |
ISSN: | 1087-0547 |
Date of First Compliant Deposit: | 15 November 2021 |
Date of Acceptance: | 14 November 2021 |
Last Modified: | 06 Nov 2024 04:15 |
URI: | https://orca.cardiff.ac.uk/id/eprint/145498 |
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