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Cell competition: Clonal competition protects against early tumorigenesis

D'Ambrogio, Joshua, Hill, Liam and Hogan, Catherine ORCID: https://orcid.org/0000-0002-1012-0896 2022. Cell competition: Clonal competition protects against early tumorigenesis. Current Biology 32 (1) , PR52-R54. 10.1016/j.cub.2021.11.029

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Abstract

Aging tissues accumulate somatic mutations, yet cancer occurrence is relatively rare. A new study provides compelling evidence for why this may be the case and reveals that competition between mutant clones in oesophageal tissues protects against early tumorigenesis.

Item Type: Article
Date Type: Published Online
Status: Published
Schools: Biosciences
European Cancer Stem Cell Research Institute (ECSCRI)
Publisher: Elsevier
ISSN: 0960-9822
Date of First Compliant Deposit: 9 February 2022
Date of Acceptance: 1 December 2021
Last Modified: 07 Nov 2023 03:31
URI: https://orca.cardiff.ac.uk/id/eprint/147360

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