A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia

Osimo, Emanuele F., Brugger, Stefan P., Thomas, E. Louise and Howes, Oliver D. 2022. A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia. npj Schizophrenia 8 (1) , 24. 10.1038/s41537-022-00233-z

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Abstract

People with schizophrenia show higher risk for abdominal obesity than the general population, which could contribute to excess mortality. However, it is unclear whether this is driven by alterations in abdominal fat partitioning. Here, we test the hypothesis that individuals with schizophrenia show a higher proportion of visceral to total body fat measured using magnetic resonance imaging (MRI). We recruited 38 participants with schizophrenia and 38 healthy controls matched on age, sex, ethnicity, and body mass index. We found no significant differences in body fat distribution between groups, suggesting that increased abdominal obesity in schizophrenia is not associated with altered fat distribution.

Item Type:	Article
Date Type:	Published Online
Status:	Published
Schools:	Psychology Cardiff University Brain Research Imaging Centre (CUBRIC)
Additional Information:	This article is licensed under a Creative Commons Attribution 4.0 International License,
Publisher:	Nature Research
ISSN:	2334-265X
Date of First Compliant Deposit:	29 March 2022
Date of Acceptance:	1 February 2022
Last Modified:	09 May 2023 02:22
URI:	https://orca.cardiff.ac.uk/id/eprint/148953

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