Between- and within-individual sociodemographic and psychological determinants of PrEP adherence among men who have sex with men prescribed a daily PrEP regimen in Wales

Gillespie, David ORCID: https://orcid.org/0000-0002-6934-2928, de Bruin, Marjin, Hughes, Dyfrig, Ma, Richard, Williams, Adam, Wood, Fiona ORCID: https://orcid.org/0000-0001-7397-4074, Couzens, Zoë, Jones, Adam and Hood, Kerenza ORCID: https://orcid.org/0000-0002-5268-8631 2023. Between- and within-individual sociodemographic and psychological determinants of PrEP adherence among men who have sex with men prescribed a daily PrEP regimen in Wales. AIDS and Behavior 27 , pp. 1564-1572. 10.1007/s10461-022-03890-4

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Abstract

We investigated the determinants of daily PrEP use and coverage of condomless anal sex (CAS) by PrEP among men who have sex with men in Wales, UK. We measured PrEP use by electronic monitors and CAS by secure online surveys. We defned PrEP use based on daily medication cap openings and coverage as CAS episodes preceded by≥3 days of PrEP use and followed by≥2 days of PrEP use. We included 57 participants (5463 observations). An STI diagnosis was associated with lower PrEP use but also lower PrEP coverage. Older adults had higher PrEP use. A belief that other PrEP users took PrEP as prescribed was associated with lower PrEP coverage. An STI diagnosis is an important cue for an intervention, refecting episodes of high-risk sexual behaviour and low PrEP coverage. Other results provide a basis for the development of an evidence-informed intervention for promoting coverage of PrEP

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine Centre for Trials Research (CNTRR)
Publisher:	Springer
ISSN:	1573-3254
Funders:	Cancer Research UK, Health and Care Research Wales
Date of First Compliant Deposit:	7 October 2022
Date of Acceptance:	3 October 2022
Last Modified:	21 Aug 2024 09:44
URI:	https://orca.cardiff.ac.uk/id/eprint/153138

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