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PEARLS - A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA-avid pelvic and/or para-aortic lymph nodes at presentation

Murray, Julia, Cruickshank, Clare, Bird, Thomas, Bell, Philip, Braun, John, Chuter, Dave, Ferreira, Miguel Reis, Griffin, Clare, Hassan, Shama, Hujairi, Nabil, Melcher, Alan, Miles, Elizabeth, Naismith, Olivia, Panades, Miguel, Philipps, Lara, Reid, Alison, Rekowski, Jan, Sankey, Pete, Staffurth, John ORCID: https://orcid.org/0000-0002-7834-3172, Syndikus, Isabel, Tree, Alison, Wilkins, Anna and Hall, Emma 2022. PEARLS - A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA-avid pelvic and/or para-aortic lymph nodes at presentation. Clinical and Translational Radiation Oncology 37 , pp. 130-136. 10.1016/j.ctro.2022.09.003

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Abstract

PEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the para-aortic lymph nodes (up to L1/L2 vertebral interspace) can improve outcomes for this patient group.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Elsevier
ISSN: 2405-6308
Date of First Compliant Deposit: 17 March 2023
Date of Acceptance: 18 September 2022
Last Modified: 17 May 2023 04:59
URI: https://orca.cardiff.ac.uk/id/eprint/157782

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