The predictive power of autobiographical memory in shaping the mental health of young people: An individual participant data meta-analysis

Doan, Uyen, Hong, Dou, Shiels Mares, Leo, Butler, Molly, Dahl Askelund, Adrian, Gutenbrunner, Charlotte, Hiller, Rachel, Nixon, Reginald, Puetz, Vanessa, Jose, Paul, Metts, Alison, Alloy, Lauren, Gibb, Brandon, Hipwell, Alison, Salmon, Karen, Powell, Victoria, Naomi, Warne, Rice, Frances ORCID: https://orcid.org/0000-0002-9484-1729 and Hitchcock, Caitlin 2025. The predictive power of autobiographical memory in shaping the mental health of young people: An individual participant data meta-analysis. Psychological Bulletin

PDF - Accepted Post-Print Version Download (684kB)

Abstract

Reduced autobiographical memory (AM) specificity, characterized by difficulty recalling specific past events, is a feature of multiple psychiatric disorders. While meta-analyses indicate that reduced AM specificity can predict future symptom severity, its role as a premorbid risk factor for mental illness onset in young people remains unclear. Our pre-registered individual participant data meta-analysis (PROSPERO; CRD42022287786) synthesized longitudinal data from 14 community-based studies of children and adolescents (N = 9165). Most studies reported symptom severity (92.9%), with one-third also reporting diagnostic status (35.7%). Assessment timing ranged from 2 months to 8.3 years following the Autobiographical Memory Task. Multivariate mixed-effect models found no support for AM specificity predicting future symptom severity in depression or post-traumatic stress disorder. Contrary to expectations, higher memory specificity significantly predicted higher anxiety symptoms, but the quality of evidence was low. Intriguingly, reduced AM specificity significantly predicted an increased risk of receiving a psychiatric diagnosis, and an earlier onset of disorder (hazard ratio = 0.55, p = .018). This risk was most robust for depressive disorders (hazard ratio = 0.21, p < .001). Findings suggest reduced AM specificity could be a risk factor for the onset of functionally impairing psychiatric disorders, but it does not consistently predict elevated symptoms in community-based samples. Further theoretical development is needed.

Item Type:	Article
Status:	In Press
Schools:	Schools > Medicine
Publisher:	American Psychological Association
ISSN:	0033-2909
Date of First Compliant Deposit:	26 February 2025
Date of Acceptance:	12 February 2025
Last Modified:	26 Feb 2025 13:00
URI:	https://orca.cardiff.ac.uk/id/eprint/176270

Actions (repository staff only)

Edit Item