Cell regeneration therapy as an adjunct to healing in recalcitrant wounds [Abstract]

Cairns, Scott, Leaper, David J. and Harding, Keith Gordon 2008. Cell regeneration therapy as an adjunct to healing in recalcitrant wounds [Abstract]. Wound Repair and Regeneration 16 (6) , A78. 10.1111/j.1524-475X.2008.00424.x

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Abstract

Background: Chronic wounds have for many centuries represented a major source of morbidity and mortality in patients. In the modern era we realise that these wounds also produce a major psychological impact to the patients, and a financial burden to the healthcare systems around the world. Ever since the first skin grafts were attempted in India around 2000bc for the reconstruction of punitatively amputated noses, the surgical profession and medical sciences have been searching for the panacea to treat chronic wounds. Yet as our understanding of the aetiology of chronic wounds deepens we realise that the varied nature of the wound pathogenesis means there will never be a ‘‘one cure for all’’ treatment. In this way we can see that a split skin graft is certainly not the optimal option for many patients, and that alternatives must be found. Method: In two selected patients with chronic static laparotomy wounds we demonstrate the successful use of a biological tissue regeneration therapy (Apligraf s) in the management of these recalcitrant wounds. Conclusion: In carefully selected patients under the care of a Multidisciplinary Wound Healing Team, the use of cell based tissue regeneration products may provide a valuable adjunct to standard wound healing regimens.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Additional Information:	Poster abstract for European Tissue Repair Society: Joint Meeting with the Tissue Viability Unit of Malta.
Publisher:	Wiley-Blackwell
ISSN:	1067-1927
Last Modified:	06 Jan 2018 20:19
URI:	https://orca.cardiff.ac.uk/id/eprint/17644

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