Modelling the response of whispering-gallery-mode optical resonators for biosensing applications

Langbein, Wolfgang Werner ORCID: https://orcid.org/0000-0001-9786-1023, Chantada, Laura, Nikolaev, Nickolay I., Ivanov, Alex and Borri, Paola ORCID: https://orcid.org/0000-0002-7873-3314 2009. Modelling the response of whispering-gallery-mode optical resonators for biosensing applications. Presented at: International Conference on Transparent Optical Networks (ICTON), São Miguel, Azores, Portugal, 28 June - 2 July 2009. Proceedings of the11th International Conference on Transparent Optical Networks (ICTON '09), Azores, 28 June - 2 July 2009. Piscataway, NJ: Institute of Electrical and Electronics Engineers, p. 1. 10.1109/ICTON.2009.5185173

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Abstract

In recent years, sharp photonic resonances of dielectric microspheres, so-called whispering gallery modes (WGMs), have emerged as powerful transducer for sensing applications. The long photon lifetime of the modes together with the small surface area of the microresonator is promising for their use as sensitive probes of changes in the surrounding medium. In this work we present a theoretical analysis of the response of WGMs for biosensing applications, studied numerically in microcylinders and semi-analytically in microspheres. In both cases, we consider a layout where WGMs are excited via frustrated total internal reflection from a planar substrate, as reported in recent experiments. The effect of single and multiple particles is calculated, simulating biological analytes of different sizes and polarizabilities attached to the microresonator surface. For microcylinders, cylinder-shaped particle are considered, to retain a 2D numerical problem. Besides WGM frequency shifts, we find that also broadenings and splittings (from lifted rotational symmetry) appear due to particles attachment and/or the vicinity to the planar substrate. In particular, for a single analyte, both particle size and refractive index can be determined from the WGM broadening and shift, opening the perspective to a new biosensing modality. In microspheres, a perturbation method is used to model shifts and splittings of WGMs in the presence of point-like particles and global shape perturbations. Due to the large azimuthal degeneracy of the modes without perturbation, the resulting mode spectrum is rich and offers a fingerprint of the perturbation.

Item Type:	Conference or Workshop Item (Paper)
Date Type:	Publication
Status:	Published
Schools:	Physics and Astronomy Biosciences
Subjects:	Q Science > QC Physics Q Science > QH Natural history > QH301 Biology
Uncontrolled Keywords:	microcylinders , microspheres , optical resonators , particle sensing , shape perturbation , whispering gallery modes
Publisher:	Institute of Electrical and Electronics Engineers
ISBN:	978142444828
Last Modified:	06 Feb 2023 15:31
URI:	https://orca.cardiff.ac.uk/id/eprint/27559

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