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Migraine in recurrent depression: case-control study (Paper)

Samaan, Zainab, Farmer, Anne, Craddock, Nicholas John, Jones, Lisa, Korszun, Ania, Owen, Michael John and McGuffin, Peter 2009. Migraine in recurrent depression: case-control study (Paper). British Journal of Psychiatry 194 (4) , pp. 350-354. 10.1192/bjp.bp.108.054049

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Background An association between depression and headache is well established, but the specificity to migraine is unclear. Aims To investigate the specificity of the association of depression and migraine. Method People with recurrent depression (n=1259) were compared with psychiatrically healthy controls (n=851) to investigate headache defined according to International Headache Society criteria in each group. Results All headache types were more prevalent in the case group than in the controls. However, the strongest association was between depression and migraine with aura (OR=5.6). Among participants with recurrent headaches, migraine with aura (but not other forms of headache) was highly significantly associated with depression. Conclusions The data suggest that not only is there a general relationship between headache and depression but also that among people with recurrent headache there is a specific association between depression and migraine with aura. The association is likely to be explained by overlapping aetiological risk factors.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Publisher: Royal College of Psychiatrists
ISSN: 0007-1250
Last Modified: 04 Jun 2017 03:54

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