Bicyclic 5-6 Systems: Four Heteroatoms 1:3

Elliott, Mark Christopher ORCID: https://orcid.org/0000-0003-0132-0818 2008. Bicyclic 5-6 Systems: Four Heteroatoms 1:3. Jones, Raymond C. F., ed. Comprehensive Heterocyclic Chemistry III, Vol. 10. Amsterdam: Elsevier, pp. 493-509. (10.1016/B978-008044992-0.00909-3)

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Abstract

This chapter reviews the synthesis and reactions of heterocyclic compounds consisting of a 6-5 fused system with three heteroatoms in the six-membered ring and one in the five-membered ring. A wide range of compounds of this type have been reported between 1995 and 2007. The most prominent group of compounds are ribose derivatives in which the 3-hydroxy and 4-hydroxymethyl groups are tethered with phosphorus, sulfur, or silicon. Coverage of the cyclic phosphate derivatives is restricted to structural studies. Various isomers of thieno-thiadiazines have been studied due to their psychotropic and potassium channel activity. The synthesis and reactions of other compounds containing the requisite ring sizes and heteroatoms are also reviewed.

Item Type:	Book Section
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Subjects:	Q Science > QD Chemistry
Uncontrolled Keywords:	Curtius rearrangement; Deoxyribose; Isocyanate; Nucleoside; Pyrrole-triazine; Ribose; Thieno-thiadiazine; Thionucleoside; Trioxane
Publisher:	Elsevier
ISBN:	9780080450025
Last Modified:	21 Oct 2022 10:18
URI:	https://orca.cardiff.ac.uk/id/eprint/39785

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