P74 A novel measure of physical exercise capacity in COPD [Poster]

Albarrati, Ali ORCID: https://orcid.org/0000-0002-6666-1157, Gale, Nichola S. ORCID: https://orcid.org/0000-0001-5207-9863, Duckers, J., Enright, Stephanie, Munnery, Iain C., Munnery, Margaret, Cockcroft, John Ronald and Shale, Dennis 2012. P74 A novel measure of physical exercise capacity in COPD [Poster]. Thorax 67 (S2) , A96. 10.1136/thoraxjnl-2012-202678.316

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Abstract

Introduction Chronic obstructive pulmonary disease (COPD) is associated with progressive impairment of physical performance. However, determination of physical performance in routine clinical practise is difficult due to limited resources. This study compared the timed up and go (TUG) test and a range of assessments of physical performance, easily applied in the routine care of COPD, with the 6 minute walk test (6MWT). Method As part of a longitudinal study of comorbidities in COPD, sub-maximal physical performance was examined in 300 patients and 50 comparators using the 6MWT. The TUG test, spirometry, COPD assessment test (CAT), St George’s Respiratory Questionnaire (SGRQ) and gait speed were also determined. Gait speed was determined by dividing 6MWTd istance by time. Results Patients and comparators were similar in age, BMI and gender. There were between group differences in 6MWT, TUG and gait speed (Table 1), ANOVA showed a difference between comparators and the GOLD stages of COPD for all these variables (all p<0.01). The TUG time differed across BMI categories in COPD but not comparators (ANOVA p=0.007 and p=0.195 respectively). The TUG time was inversely related to 6MWT (r=0.64, p<0.0001), gait speed (r=0.63, p<0.0001)and lung function (r=0.15, p<0.01), and directly to the activity (r=0.35, p<0.0001)and total SGRQ scores (r=0.35, p<0.0001) and CAT (r=0.39, p<0.0001). Stepwise regression analysis, adjusted for age and BMI, indicated that TUG time, SGRQ activity score and CAT score explained 73% of variance in 6MWT in patients, with lung function excluded from the analysis.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Healthcare Sciences
Subjects:	R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RZ Other systems of medicine
Publisher:	British Thoracic Society
ISSN:	0040-6376
Last Modified:	21 Oct 2022 10:55
URI:	https://orca.cardiff.ac.uk/id/eprint/41746

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