Alchemist multimodal workflows for diabetic retinopathy research, disease prevention and investigational drug discovery

Riposan, Adina, Taylor, Ian James ORCID: https://orcid.org/0000-0001-5040-0772, Owens, David R., Rana, Omer Farooq ORCID: https://orcid.org/0000-0003-3597-2646 and Conley, Edward C. 2007. Alchemist multimodal workflows for diabetic retinopathy research, disease prevention and investigational drug discovery. Presented at: 5th Health Grid Conference 2007, Geneva, Switzerland, 24-27 April 2007. From Genes to Personalized HealthCare: Grid Solutions for the Life Sciences: Proceedings of HealthGrid 2007. Studies in Health Technology and Informatics (126) Amsterdam: IOS Press, pp. 279-288.

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Abstract

In this paper we present mechanisms for imaging and spectral data discovery, as applied to the early detection of pathologic mechanisms underlying diabetic retinopathy in research and clinical trial scenarios. We discuss the Alchemist framework, built using a generic peer-to-peer architecture, supporting distributed database queries and complex search algorithms based on workflow. The Alchemist is a domain-independent search mechanism that can be applied to search and data discovery scenarios in many areas.We illustrate Alchemist’s ability to perform complex searches composed as a collection of peer-to-peer overlays, Grid-based services and workflows, e.g. applied to image and spectral data discovery, as applied to the early detection and prevention of retinal disease and investigational drug discovery. The Alchemist framework is built on top of decentralised technologies and uses industry standards such as Web services and SOAP for messaging.

Item Type:	Conference or Workshop Item (Paper)
Date Type:	Publication
Status:	Published
Schools:	Computer Science & Informatics
Subjects:	Q Science > QA Mathematics > QA75 Electronic computers. Computer science
Uncontrolled Keywords:	Biomedical Informatics, Biomedical integration, Biomedical imaging, Spectroscopy, Diabetic Retinopathy, Search engine, Resource discovery, Grid, HealthGrid, P2P, peer-to-peer, WS-RF, WSPeer, Ubiquitous computing
Publisher:	IOS Press
ISBN:	9781586037383
Related URLs:	Publisher
Last Modified:	14 Dec 2022 03:12
URI:	https://orca.cardiff.ac.uk/id/eprint/45837

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