Cytokine blockade in rheumatoid arthritis

Feldmann, Marc, Maini, Ravinder N., Bondeson, Jan, Taylor, Peter, Foxwell, Brian M. J. and Brennan, Fionula M. 2001. Cytokine blockade in rheumatoid arthritis. Advances in Experimental Medicine and Biology 490 , pp. 119-127. 10.1007/978-1-4615-1243-1_13

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Abstract

As we enter the 2000’s it is clear that cytokine blockade is an effective therapeutic strategy for rheumatoid arthritis. In this brief review, we will review the rationale for anti TNFa therapy, the current status of therapy and focus on the regulation of TNFa production in rheumatoid synovium. New approaches to studying TNF regulation in RA and of elucidating the controversial role of T cells in this complex disease will be described.

Item Type:	Article
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Springer
ISSN:	0065-2598
Last Modified:	30 Jun 2017 03:25
URI:	https://orca.cardiff.ac.uk/id/eprint/57183

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