The genome of equine herpesvirus type 2 harbors an interleukin 10 (IL10)-like gene

Rode, Hans-Jürgen, Janssen, Waltraud, Rösen-Wolff, Angela, Bugert, Joachim Jakob ORCID: https://orcid.org/0000-0002-0556-3211, Thein, Peter, Becker, Yechiel and Darai, Gholamreza 1993. The genome of equine herpesvirus type 2 harbors an interleukin 10 (IL10)-like gene. Virus Genes 7 (1) , pp. 111-116. 10.1007/BF01702353

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Abstract

A gene was identified within the DNA sequences of theEcoRI DNA fragment N (4.3 kbp) of the genome of equine herpesvirus type 2 (EHV-2) coding for a protein (179 amino acid residues) homologous to the cytokine synthesis inhibitory factor (CSIF; interleukin 10) of the human and mouse, and to the Epstein-Barr virus (EBV) protein BCRF1. This finding is further significant evidence that the interleukin 10 (IL-10) and/or IL-10-like gene can indeed be present in the genomes of members of the herpesviral family.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	Q Science > QR Microbiology > QR180 Immunology R Medicine > R Medicine (General)
Publisher:	Springer
ISSN:	0920-8569
Last Modified:	25 Oct 2022 09:18
URI:	https://orca.cardiff.ac.uk/id/eprint/57998

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