3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria

Amoroso, Angelo James ORCID: https://orcid.org/0000-0002-7601-5482, Arthur, Richard John, Coogan, Michael Peter, Court, Jonathan B., Fernández-Moreira, Vanesa ORCID: https://orcid.org/0000-0002-1218-7218, Hayes, Anthony Joseph, Lloyd, David ORCID: https://orcid.org/0000-0002-5656-0571, Millet, Coralie Ode and Pope, Simon J. A. ORCID: https://orcid.org/0000-0001-9110-9711 2008. 3-Chloromethylpyridyl bipyridine fac-tricarbonyl rhenium: a thiol-reactive luminophore for fluorescence microscopy accumulates in mitochondria. New Journal of Chemistry 32 (7) , pp. 1097-1102. 10.1039/b802215a

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Abstract

The 3-chloromethylpyridyl bipyridine fac tricarbonyl rhenium cation is a thiol-reactive luminescent agent with a long luminescence lifetime and large Stokes shift that is demonstrated by co-localisation studies to accumulate in mitochondria. This represents the first application of a 3MLCT luminescent agent for the specific targeting of a biological entity in imaging.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry Biosciences
Publisher:	Royal Society of Chemistry
ISSN:	1144-0546
Last Modified:	17 Oct 2022 09:49
URI:	https://orca.cardiff.ac.uk/id/eprint/5842

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