Ca2+ signalling and Ca2+-activated ion channels in exocrine acinar cells

Petersen, Ole Holger ORCID: https://orcid.org/0000-0002-6998-0380 2005. Ca2+ signalling and Ca2+-activated ion channels in exocrine acinar cells. Cell Calcium 38 (3-4) , pp. 171-200. 10.1016/j.ceca.2005.06.024

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Abstract

The development of the calcium signalling field, from its early beginnings some 40 years ago to the present, is described. Calcium signalling in exocrine gland acinar cells and the effects of neurotransmitter- or hormone-elicited rises in the cytosolic calcium ion concentration on ion channel gating are reviewed. The highly polarized arrangement of the organelle systems in living acinar cells is described as well as its importance for the physiologically relevant local and polarized calcium signalling events.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences Systems Immunity Research Institute (SIURI)
Uncontrolled Keywords:	Calcium-activated ion channels; Calcium oscillations; IP3 receptors; Ryanodine receptors; NAADP; cADPR
Additional Information:	Special issue: Frontiers in calcium signalling
Publisher:	Elsevier
ISSN:	0143-4160
Last Modified:	27 Oct 2022 08:41
URI:	https://orca.cardiff.ac.uk/id/eprint/63129

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