No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms

Craddock, Nicholas John ORCID: https://orcid.org/0000-0003-2171-0610, Daniels, J., Roberts, E., Rees, M., McGuffin, P. and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 1995. No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms. American Journal of Medical Genetics 60 (4) , pp. 322-324. 10.1002/ajmg.1320600412

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Abstract

We have tested the hypothesis that DNA markers in the MAOA gene show allelic association with bipolar affective disorder. Eighty-four unrelated Caucasian patients with DSM III-R bipolar disorder and 84 Caucasian controls were typed for three markers in MAOA: a dinucleotide repeat in intron 2, a VNTR in intron 1, and an Fnu4HI RFLP in exon 8. No evidence for allelic association was observed between any of the markers and bipolar disorder.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine Research Institutes & Centres > MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) Research Institutes & Centres > Neuroscience and Mental Health Research Institute (NMHII)
Subjects:	R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine
Publisher:	Wiley
ISSN:	0148-7299
Last Modified:	27 Oct 2022 08:48
URI:	https://orca.cardiff.ac.uk/id/eprint/63437

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