Comparison of the antioxidant properties of HYAFF-11p75, AQUACEL and hyaluronan towards reactive oxygen species in vitro

Moseley, Ryan ORCID: https://orcid.org/0000-0002-2812-6735, Leaver, M., Waddington, Rachel J. ORCID: https://orcid.org/0000-0001-5878-1434, Walker, M., Parsons, D., Chen, W.Y.J. and Embery, Graham 2002. Comparison of the antioxidant properties of HYAFF-11p75, AQUACEL and hyaluronan towards reactive oxygen species in vitro. Biomaterials 23 (10) , pp. 2255-2264. 10.1016/S0142-9612(01)00360-X

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Abstract

In chronic wounds, a number of host factors are released which perpetuate the inflammatory process, including polymorphonuclear leukocyte (PMN)-derived reactive oxygen species (ROS), such as superoxide radical (O2??) and hydroxyl radical (?OH) species. The glycosaminoglycan, hyaluronan, has been shown to act as an antioxidant towards ROS, although the potential for biomaterials, such as HYAFF

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Dentistry
Uncontrolled Keywords:	Reactive oxygen species ; Hyaluronan ; Hyaff®-11p75 ; Aquacel® ; Antioxidants ; Chronic wounds
ISSN:	01429612
Last Modified:	17 Oct 2022 08:39
URI:	https://orca.cardiff.ac.uk/id/eprint/681

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