No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia

Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862, Mant, R., Parfitt, E., Williams, Julie ORCID: https://orcid.org/0000-0002-4069-0259, Asherson, P., O'Mahoney, G., Van Os, J., Llewellyn, D., Collier, D., Gill, M. and McGuffin, P. 1992. No association between RFLPs at the porphobilinogen deaminase gene and schizophrenia. Human Genetics 90 (1-2) , pp. 131-132. 10.1007/BF00210756

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Abstract

An association study of restriction fragment length polymorphisms (RFLPs) in the porphobilinogen deaminase (PBGD) gene and schizophrenia was conducted. RFLPs detected by MspI, PstI, ApaLI and BstNI in intron 1 of the gene were studied in 49 patients and 79 controls. There were no significant differences between the groups in allele frequencies, genotype counts or haplotype distribution.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) Medicine Neuroscience and Mental Health Research Institute (NMHRI)
Subjects:	R Medicine > R Medicine (General)
Publisher:	Springer
ISSN:	0340-6717
Last Modified:	31 Oct 2022 09:23
URI:	https://orca.cardiff.ac.uk/id/eprint/80874

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