Basra, M.K.A., Salek, M.S., Camilleri, L., Sturkey, R. and Finlay, Andrew Yule ORCID: https://orcid.org/0000-0003-2143-1646 2015. Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data. Dermatology 230 (1) , pp. 27-33. 10.1159/000365390 |
Abstract
Aims: To determine the minimal clinically important difference (MCID) of the Dermatology Life Quality Index (DLQI) and its responsiveness to change in inflammatory skin diseases. Methods: A longitudinal study: at stage 1, patients completed the DLQI and a disease severity global question; at stage 2, a global rating of change in quality of life (QoL; Global Rating of Change Questionnaire, GRCQ) was added and used as an anchor to measure the MCID of the DLQI. Results: 192 patients completed stage 1 and 107 completed stage 2. The mean DLQI score at stage 1 was 9.8 and 7.4 at stage 2 with a mean change of 2.4 (p < 0.0001). 31 patients experienced a ‘small change' in their QoL (±3 and ±2) on the GRCQ. The mean corresponding change in DLQI scores was 3.3, which is regarded as the approximate MCID. Conclusions: Previous estimates of the MCID of the DLQI have varied from 3 to 5. Although this study demonstrated a MCID of 3.3, we recommend that the MCID in inflammatory skin diseases should be 4.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Medicine |
Subjects: | R Medicine > R Medicine (General) R Medicine > RL Dermatology |
Uncontrolled Keywords: | DLQI, MCID, Responsiveness, Minimum clinically important difference, Skin disease |
Publisher: | Karger |
ISSN: | 1018-8665 |
Date of Acceptance: | 19 June 2014 |
Last Modified: | 31 Oct 2022 10:22 |
URI: | https://orca.cardiff.ac.uk/id/eprint/84592 |
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