Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?

Morris, I, Lyttle, M D, O'Sullivan, R, Sargant, N, Doull, Iolo John Manley and Powell, Colin Victor Eric 2014. Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland? Thorax 70 (1) , pp. 88-91. 10.1136/thoraxjnl-2014-206041

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Abstract

During a prospective 10-week assessment period, 3238 children aged 1–16 years presented with acute wheeze to Paediatric Emergency Research in the UK and Ireland centres. 110 (3.3%) received intravenous bronchodilators. Intravenous magnesium sulfate (MgSO4) was used in 67 (60.9%), salbutamol in 61 (55.5%) and aminophylline in 52 (47.3%) of cases. In 35 cases (31.8%), two drugs were used together, and in 18 cases (16.4%), all three drugs were administered. When used sequentially the most common order was salbutamol, then MgSO4, then aminophylline. Overall, 30 different intravenous treatment regimens were used varying in drugs, dose, rate and duration.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RJ Pediatrics
Publisher:	BMJ Publishing Group Ltd
ISSN:	0040-6376
Date of Acceptance:	26 September 2014
Last Modified:	11 Jun 2019 12:34
URI:	https://orca.cardiff.ac.uk/id/eprint/84808

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