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Segmental cherry angiomas associated with extragenital lichen sclerosus: a report of two cases

Ingram, John R., Belgi, G., Cook, L. J., Hughes, B. R., Karim, A. and Finlay, Andrew Yule 2013. Segmental cherry angiomas associated with extragenital lichen sclerosus: a report of two cases. Clinical and Experimental Dermatology 38 (4) , pp. 386-389. 10.1111/j.1365-2230.2012.04479.x

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Cherry angiomas (Campbell de Morgan spots) are common acquired red skin papules composed of dilated capillary loops, usually of unknown aetiology. Extragenital lichen sclerosus (LS) presents as porcelain-white scaly atrophic lesions with or without genital involvement. We report two cases of segmental multiple cherry angiomas in association with extragenital LS. Two unrelated women, aged 46 and 66 years, presented with extragenital LS affecting their axillae and lower abdomen. During the examination, both patients were noted to have several hundred red skin papules in a segmental distribution, affecting the left thigh and flank of one woman, and the right abdomen and back of the other. Clinically and histologically, the papules were consistent with cherry angiomas. The striking segmental distribution of multiple cherry angiomas may be due to genetic mosaicism; however, segmental Fabry disease was excluded by sequence analysis of the α-galactosidase A gene. Any causal link between cherry angiomas and LS remains uncertain.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > RL Dermatology
Publisher: Wiley-Blackwell
ISSN: 0307-6938
Last Modified: 15 Dec 2017 11:47

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