Temporal lobe contribution to perceptual function: A tale of three patient groups

Behrmann, M., Lee, A. C. H., Geskin, J. Z., Graham, Kim Samantha ORCID: https://orcid.org/0000-0002-1512-7667 and Barense, M. D. 2016. Temporal lobe contribution to perceptual function: A tale of three patient groups. Neuropsychologia 90 , pp. 33-45. 10.1016/j.neuropsychologia.2016.05.002

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Abstract

There has been growing recognition of the contribution of medial and anterior temporal lobe structures to non-mnemonic functions, such as perception. To evaluate the nature of this contribution, we contrast the perceptual performance of three patient groups, all of whom have a perturbation of these temporal lobe structures. Specifically, we compare the profile of patients with focal hippocampal (HC) lesions, those with more extensive lesions to the medial temporal lobe (MTL) that include HC and perirhinal cortex (PrC), and those with congenital prosopagnosia (CP), whose deficit has been attributed to the disconnection of the anterior temporal lobe from more posterior structures. All participants completed a range of'oddity’ tasks in which, on each trial, they determined which of four visual stimuli in a display was the'odd-one-out’. There were five stimulus categories including faces, scenes, objects (high and low ambiguity) and squares of different sizes. Comparisons were conducted separately for the HC, MTL and CP groups against their matched control groups and then the group data were compared to each other directly. The group profiles were easily differentiable. Whereas the HC group stood out for its difficulty in discriminating scenes and the CP group stood out for its disproportionate difficulty in discriminating faces with milder effects for scenes and high ambiguity objects, the MTL group evinced a more general discrimination deficit for faces, scenes and high ambiguity objects. The group differences highlight distinct profiles for each of the three groups and distinguish the signature perceptual impairments following more extended temporal lobe alterations.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Psychology
Subjects:	R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Uncontrolled Keywords:	Perception; Medial temporal lobe; Amnesia; Hippocampus; Perirhinal cortex; Congenital prosopagnosia; Visual discrimination
Publisher:	Elsevier
ISSN:	0028-3932
Funders:	MRC, BBSRC
Date of First Compliant Deposit:	9 May 2016
Date of Acceptance:	2 May 2016
Last Modified:	08 Nov 2023 00:48
URI:	https://orca.cardiff.ac.uk/id/eprint/90717

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