Fast optimisation of a Diels-Alder reaction in a flow microreactor by in-line HPLC analysis

Rasheed, Munawwer and Wirth, Thomas ORCID: https://orcid.org/0000-0002-8990-0667 2011. Fast optimisation of a Diels-Alder reaction in a flow microreactor by in-line HPLC analysis. Chimica Oggi - Chemistry Today 29 (3) , pp. 53-55.

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Abstract

A continuous-flow micro reactor is used for Diels-Alder reactions. Its direct in-line connection to an HPLC allows the analysis and optimization of the reaction on a much shorter time scale than performing the corresponding reactions under batch reaction conditions. A large number of experiments are performed in a short time with minimal reagent consumption. Together with very small volumes of solvents, such an approach provides a green, economical and safe environment for reaction screening.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry
Subjects:	Q Science > QD Chemistry
Publisher:	TEKNOSCIENZE
Last Modified:	18 Oct 2022 12:26
URI:	https://orca.cardiff.ac.uk/id/eprint/9804

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