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Allergen immunotherapy for insect venom allergy: protocol for a systematic review

Dhami, Sangeeta, Nurmatov, Ulugbek ORCID:, Varga, Eva‑Maria, Sturm, Gunter, Muraro, Antonella, Akdis, Cezmi A., Antolín‑Amérigo, Darío, Bilò, M. Beatrice, Bokanovic, Danijela, Calderon, Moises A., Cichocka‑Jarosz, Ewa, Oude Elberink, Joanna N. G., Gawlik, Radoslaw, Jakob, Thilo, Kosnik, Mitja, Lange, Joanna, Mingomataj, Ervin, Mitsias, Dimitris I., Mosbech, Holger, Pfaar, Oliver, Pitsios, Constantinos, Pravettoni, Valerio, Roberts, Graham, Ruëff, Franziska, Ayşe Sin, Betül and Sheikh, Aziz 2016. Allergen immunotherapy for insect venom allergy: protocol for a systematic review. Clinical and Translational Allergy 6 (6) 10.1186/s13601-016-0095-x

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Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Insect Venom Allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of insect venom allergy. Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. Discussion: The findings from this review will be used to inform the development of recomendations for EAACI’s Guidelines on AIT.

Item Type: Article
Date Type: Published Online
Status: Published
Schools: Cardiff University Brain Research Imaging Centre (CUBRIC)
Subjects: R Medicine > R Medicine (General)
Additional Information: © 2016 Dhami et al. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Publisher: Biomed Central
ISSN: 2045-7022
Date of First Compliant Deposit: 23 August 2017
Date of Acceptance: 11 January 2016
Last Modified: 05 May 2023 03:02

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