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Translation and cross-cultural adaptation with preliminary validation of GCOS-24 for use in Spain

Muñoz-Cabello, Patricia, Garcia-Minaur, Sixto, Espinel-Vallejo, Manuel Eliecer, Fernández-Franco, Lorenzo, Stephens, Alexandra, Santos-Simarro, Fernando, Lapunzina-Badia, Pablo and McAllister, Marion 2018. Translation and cross-cultural adaptation with preliminary validation of GCOS-24 for use in Spain. Journal of Genetic Counselling 27 (3) , pp. 732-743. 10.1007/s10897-017-0154-z

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The aim in this study was to translate and cross-culturally adapt the Genetic Counseling Outcome Scale (GCOS-24) for use in Spain and to carry out a preliminary psychometric validation in a sample of Spanish patients. With oversight by an expert panel, forward and backward translations were conducted to create the draft Spanish GCOS-24. Fourteen patients were recruited from a clinical genetics service in Madrid, Spain to participate in cognitive interviews designed to explore readability and interpretability of the draft. Following qualitative analysis of interview transcripts, a final version of the Spanish GCOS-24 was agreed with the expert panel. No significant cross-cultural differences were identified. The Spanish GCOS-24 was then completed prior to and 2-4 weeks after genetic counseling by 59 patients attending the service, and data were analysed using analysis of variance. Preliminary psychometric validation of the Spanish GCOS-24 showed significantly higher GCOS-24 scores after genetic counseling (p<0.0001), with good internal consistency (α=0.84) and sensitivity to change over time, with a medium-to-large size effect (Cohen ́s d=0.70). This compares well with the original English language GCOS-24. Findings demonstrate that the Spanish GCOS-24 has potential for use in evaluating clinical genetics services in Spain, but would benefit from assessment of test-retest reliability as well as structural and construct validity.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > RZ Other systems of medicine
Publisher: Springer
ISSN: 1059-7700
Date of First Compliant Deposit: 17 October 2017
Date of Acceptance: 31 August 2017
Last Modified: 06 Nov 2023 20:34

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