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Antenatal depression and offspring psychopathology: The influence of childhood maltreatment

Pawlby, Susan, Hay, Dale F. ORCID:, Sharpe, Deborah, Waters, Cerith S. ORCID: and Pariante, Carmine M. 2011. Antenatal depression and offspring psychopathology: The influence of childhood maltreatment. The British Journal of Psychiatry 199 (2) , pp. 106-112. 10.1192/bjp.bp.110.087734

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Background: Antenatal depression and childhood maltreatment have each been associated with offspring psychopathology, but have never been examined in the same sample. Aims: To determine whether childhood maltreatment influences the association between antenatal depression and offspring psychopathology. Method: Prospectively collected data on antenatal depression, offspring maltreatment (age 11) and offspring psychopathology (age 11 and 16) were analysed in 120 mother–offspring dyads from the community-based South London Child Development Study. Results: Antenatal depression increased the risk of maltreatment in the offspring by almost four times. Children exposed only to antenatal depression or only to childhood maltreatment were no more at risk of developing psychopathology; however, children exposed to both antenatal depression and childhood maltreatment were at almost 12 times greater risk of developing psychopathology than offspring not so exposed. Conclusions: Research investigating exposure to adverse events in utero and offspring psychopathology should take account of postnatal adverse events such as maltreatment.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Publisher: Royal College of Psychiatrists
ISSN: 0007-1250
Last Modified: 18 Oct 2022 12:54

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