Cao, Qun ![]() ![]() ![]() |
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License URL: http://creativecommons.org/licenses/by/4.0
License Start date: 18 September 2018
Official URL: http://dx.doi.org/10.1039/C8OB01781F
Abstract
An operationally simple mechanochemical method for the Pd catalysed Buchwald–Hartwig amination of arylhalides with secondary amines has been developed using a Pd PEPPSI catalyst system. The system is demonstrated on 30 substrates and applied in the context of a target synthesis. Furthermore, the performance of the reaction under aerobic conditions has been probed under traditional solution and mechanochemical conditions, the observations are discussed herein.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Publisher: | Royal Society of Chemistry |
ISSN: | 1477-0520 |
Funders: | EPSRC |
Date of First Compliant Deposit: | 23 October 2018 |
Date of Acceptance: | 3 September 2018 |
Last Modified: | 09 May 2023 04:16 |
URI: | https://orca.cardiff.ac.uk/id/eprint/116117 |
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Cited 42 times in Scopus. View in Scopus. Powered By Scopus® Data
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