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Dpp/BMP signaling in flies: From molecules to biology

Hamaratoglu Dion, Fisun, Affolter, Markus and Pyrowolakis, George 2014. Dpp/BMP signaling in flies: From molecules to biology. Seminars in Cell and Developmental Biology 32 , pp. 128-136. 10.1016/j.semcdb.2014.04.036

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Decapentaplegic (Dpp), the fly homolog of the secreted mammalian BMP2/4 signaling molecules, is involved in almost all aspects of fly development. Dpp has critical functions at all developmental stages, from patterning of the eggshell to the determination of adult intestinal stem cell identity. Here, we focus on recent findings regarding the transcriptional regulatory logic of the pathway, on a new feedback regulator, Pentagone, and on Dpp's roles in scaling and growth of the Drosophila wing.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Elsevier
ISSN: 1084-9521
Date of First Compliant Deposit: 2 January 2019
Date of Acceptance: 30 April 2014
Last Modified: 25 Feb 2019 14:08

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